Description
Calcium D-Glucarate – Advanced Support for Liver Detox & Hormone Metabolism
Designs for Health® Calcium D-Glucarate is a science-based supplement designed to support the body’s natural detoxification and hormone elimination processes while contributing to overall calcium intake.
Calcium D-Glucarate is the calcium salt of D-glucaric acid, a compound produced in small amounts by the human body and found in certain plant foods such as apples, citrus fruits, broccoli, cabbage, and kale. Some individuals may benefit from higher amounts through supplementation.
How Calcium D-Glucarate Supports Detoxification
One of the liver’s primary phase II detoxification pathways is glucuronidation, a process that binds toxins, pharmaceutical compounds, and excess hormones to glucuronic acid so they can be safely eliminated through the gastrointestinal tract.
However, certain gut bacteria produce an enzyme called β-glucuronidase, which can reverse this process by breaking the bond between toxins and glucuronic acid—allowing compounds to be reabsorbed rather than excreted.
Calcium D-Glucarate is metabolized in the gut into D-glucaro-1,4-lactone, a compound that may help inhibit β-glucuronidase activity. This supports efficient elimination of toxins, hormones, bile acids, and cholesterol metabolites.
Key Benefits & Clinical Support
Supports phase II liver detoxification via glucuronidation
Helps promote healthy estrogen and hormone metabolism
Supports the elimination of environmental toxins and pharmaceuticals
May support healthy cholesterol metabolism and bile acid excretion
Provides elemental calcium to support bone health
Product Highlights
Provides 150 mg elemental calcium per 2-capsule serving
Calcium D-Glucarate USP
Suitable for vegetarians
Gluten-free, dairy-free, and soy-free
Non-GMO

